There are numerous home remedies for anal itching out there. Alternatively, you can apply an OTC licorice cream on your affected area. Learn the top 5 causes (and remedies) of anal itching. If there's itching, you can use an over-the-counter or prescription hemorrhoid creams. Also, chronic itching of the anal area may lead to feelings of embarrassment. If you are taking steroid medication or other medicines that can.